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Image of stained retina

Research Publications

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 https://www.ncbi.nlm.nih.gov/myncbi/timothy.corson.1/bibliography/public/

  1. Fei X, Kwon S, Jang J, Seo M, Yu S, Corson TW, Seo SY. Exploring the antiangiogenic and anti-inflammatory potential of homoisoflavonoids: target identification using biotin probes. Biomolecules. 2024 Jun 30;14(7):785. https://doi.org/10.3390/biom14070785

  2. Fei X, Jung S, Kwon S, Kim J, Corson TW, Seo SY. Challenges and opportunities of developing small-molecule therapies for age-related macular degeneration. Arch Pharm Res. 2024 Jun;47(6):538-557. https://doi.org/10.1007/s12272-024-01503-3

  3. Daniels AB, Sishtla KL, Bogan CM, Pierce JM, Chen SC, Xu L, Berry JL, Corson TW. Aqueous VEGF-A levels as a liquid biopsy biomarker of retinoblastoma vitreous seed response to therapy. Invest Ophthalmol Vis Sci. 2024 Jun 3;65(6):18. https://doi.org/10.1167/iovs.65.6.18

  4. Atomwise AIMS Program. AI is a viable alternative to high throughput screening: a 318-target study. Sci Rep. 2024 Apr 2;14(1):7526. https://doi.org/10.1038/s41598-024-54655-z

  5. Muniyandi A, Jensen NR, Devanathan N, Dimaras H, Corson TW. The potential of aqueous humor sampling in diagnosis, prognosis, and treatment of retinoblastoma. Invest Ophthalmol Vis Sci. 2024 Jan 2;65(1):18. https://doi.org/10.1167/iovs.65.1.18

  6. Chobisa D, Muniyandi A, Sishtla K, Corson TW, Yeo Y. Long-acting microparticle formulation of griseofulvin for ocular neovascularization therapy. Small. 2024 Mar;20(10):e2306479. https://doi.org/10.1002/smll.202306479

  7. Muniyandi A, Hartman GD, Song Y, Mijit M, Kelley MR, Corson TW. Beyond VEGF: Targeting inflammation and other pathways for treatment of retinal disease. J Pharmacol Exp Ther. 2023 Jul;386(1):15-25. https://doi.org/10.1124/jpet.122.001563

  8. Nassief SM, Amer ME, Shawky E, Sishtla K, Mas-Claret E, Muniyandi A, Corson TW, Mulholland DA, El-Masry S. Antiangiogenic pterocarpan and flavonoid constituents of Erythrina lysistemon. J Nat Prod. 2023 Apr 28;86(4):759-766. https://doi.org/10.1021/acs.jnatprod.2c00909

  9. Muniyandi A, Martin M, Sishtla K, Motolani A, Sun M, Jensen NR, Qi X, Boulton ME, Prabhu L, Lu T, Corson TW. PRMT5 is a therapeutic target in choroidal neovascularization. Sci Rep. 2023 Jan 31;13(1):1747. https://doi.org/10.1038/s41598-023-28215-w

  10. Mijit M, Liu S, Sishtla K, Hartman GD, Wan J, Corson TW, Kelley MR. Identification of novel pathways regulated by APE1/Ref-1 in human retinal endothelial cells. Int J Mol Sci. 2023 Jan 6;24(2):1101. https://doi.org/10.3390/ijms24021101

  11. Park B, Sardar Pasha SPB, Sishtla KL, Hartman GD, Qi X, Boulton ME, Corson TW. Decreased expression of soluble epoxide hydrolase suppresses murine choroidal neovascularization. Int J Mol Sci. 2022 Dec 9;23(24):15595. https://doi.org/10.3390/ijms232415595

  12. Kwon S, Lee S, Hur J, Ko K, Fei X, Jeong KW, Sishtla K, Muniyandi A, Bae M, Corson TW, Seo SY. Synthesis and structure revision of naturally occurring homoisoflavane (+)-dracaeconolide B. J Nat Prod. 2023 Jan 27;86(1):149-156. https://doi.org/10.1021/acs.jnatprod.2c00859

  13. Kim EY, Lee B, Kwon S, Corson TW, Seo SY, Lee K. Mouse pharmacokinetics and in vitro metabolism of SH-11037 and SH-11008, synthetic homoisoflavonoids for retinal neovascularization. Pharmaceutics. 2022 Oct 24;14(11):2270. https://doi.org/10.3390/pharmaceutics14112270

  14. Jensen NR, Lambert-Cheatham N, Hartman GD, Muniyandi A, Park B, Sishtla K, Corson TW. An improved method for murine laser-induced choroidal neovascularization lesion quantification from optical coherence tomography images. MethodsX. 2022 Aug 2;9:101809. https://doi.org/10.1016/j.mex.2022.101809

  15. Global Retinoblastoma Study Group. The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries. Lancet Glob Health. 2022 Aug;10(8):e1128-e1140. https://doi.org/10.1016/S2214-109X(22)00250-9

  16. Sishtla K, Lambert-Cheatham N, Lee B, Han DH, Park J, Sardar Pasha SPB, Lee S, Kwon S, Muniyandi A, Park B, Odell N, Waller S, Park IY, Lee SJ, Seo SY, Corson TW. Small-molecule inhibitors of ferrochelatase are antiangiogenic agents. Cell Chem Biol. 2022 Jun 16;29(6):1010-1023.e14. https://doi.org/10.1016/j.chembiol.2022.01.001

  17. Hartman GD, Lambert-Cheatham NA, Kelley MR, Corson TW. Inhibition of APE1/Ref-1 for neovascular eye diseases: from biology to therapy. Int J Mol Sci. 2021 Sep 24;22(19):10279. https://doi.org/10.3390/ijms221910279

  18. Jacobs B, Palmer N, Shetty T, Dimaras H, Hajrasouliha A, Jusufbegovic D, Corson TW. Patient preferences in retinal drug delivery. Sci Rep. 2021 Sep 23;11(1):18996. https://doi.org/10.1038/s41598-021-98568-7

  19. Corson TW, Hawkins SM, Sanders E, Byram J, Cruz LA, Olson J, Speidell E, Schnabel R, Balaji A, Ogbeide O, Dinh J, Hinshaw A, Cummings L, Bonds V, Nakshatri H. Building a virtual summer research experience in cancer for high school and early undergraduate students: lessons from the COVID-19 pandemic. BMC Med Educ. 2021 Aug 9;21(1):422. https://doi.org/10.1186/s12909-021-02861-y

  20. Heisel C, Yousif J, Mijiti M, Charizanis K, Brigell M, Corson TW, Kelley MR. APE1/Ref-1 as a novel target for retinal diseases. J Cell Signal. 2021;2(2):133-138. https://doi.org/10.33696/Signaling.2.044

  21. Shetty T, Park B, Corson TW. Measurement of mitochondrial respiration in the murine retina using a Seahorse extracellular flux analyzer. STAR Protoc. 2021 May 12;2(2):100533. https://doi.org/10.1016/j.xpro.2021.100533

  22. Peng M, Park B, Harikrishnan H, Jahan SN, Dai J, Rayana NP, Sugali CK, Sharma TP, Imanishi S, Imanishi Y, Corson TW, Mao W. A smartphone based method for mouse fundus imaging. Exp Eye Res. 2021 May;206:108530. https://doi.org/10.1016/j.exer.2021.108530

  23. Corson TW, Wallace DK. Modulating a summer ophthalmology research experience for medical students during the COVID-19 pandemic. Int J Med Educ. 2021 Feb 26;12:34-35. https://doi.org/10.5116/ijme.600e.c0e4

  24. Sardar Pasha SPB, Shetty T, Lambert-Cheatham NA, Sishtla K, Mathew D, Muniyandi A, Patwari N, Bhatwadekar AD, Corson TW. Retinal phenotyping of ferrochelatase mutant mice reveals protoporphyrin accumulation and reduced neovascular response. Invest Ophthalmol Vis Sci. 2021 Feb 1;62(2):36. https://doi.org/10.1167/iovs.62.2.36

  25. Doud EH, Shetty T, Abt M, Mosley AL, Corson TW, Mehta A, Yeh ES. NF-κB signaling is regulated by fucosylation in metastatic breast cancer cells. Biomedicines. 2020 Dec 12;8(12):600. https://doi.org/10.3390/biomedicines8120600

  26. Corson TW. Cancer Research in the "Chemical Biology" Section of the Journal Molecules. Molecules. 2020 Nov 12;25(22):5275. https://doi.org/10.3390/molecules25225275

  27. Shetty T, Corson TW. Mitochondrial heme synthesis enzymes as therapeutic targets in vascular diseases. Front Pharmacol. 2020 Jul 15;11:1015. https://doi.org/10.3389/fphar.2020.01015

  28. Shetty T, Sishtla K, Park B, Repass MJ, Corson TW. Heme synthesis inhibition blocks angiogenesis via mitochondrial dysfunction. iScience. 2020 Aug 21;23(8):101391. https://doi.org/10.1016/j.isci.2020.101391

  29. Barry Z, Park B, Corson TW. Pharmacological potential of small molecules for treating corneal neovascularization. Molecules. 2020 Jul 30;25(15):3468. https://doi.org/10.3390/molecules25153468

  30. Pran Babu SPS, White D, Corson TW. Ferrochelatase regulates retinal neovascularization. FASEB J. 2020 Sep;34(9):12419-12435. https://doi.org/10.1096/fj.202000964R

  31. Kwon S, Lee S, Heo M, Lee B, Fei X, Corson TW, Seo SY. Total synthesis of naturally occurring 5,7,8-trioxygenated homoisoflavonoids. ACS Omega. 2020 May 6;5(19):11043-11057. https://doi.org/10.1021/acsomega.0c00932

  32. Xu D, Zhou D, Bum-Erdene K, Bailey BJ, Sishtla K, Liu S, Wan J, Aryal UK, Lee JA, Wells CD, Fishel ML, Corson TW, Pollok KE, Meroueh SO. Phenotypic screening of chemical libraries enriched by molecular docking to multiple targets selected from glioblastoma genomic data. ACS Chem Biol. 2020 Jun 19;15(6):1424-1444. https://doi.org/10.1021/acschembio.0c00078

  33. Global Retinoblastoma Study Group. Global retinoblastoma presentation and analysis by national income level. JAMA Oncol. 2020 May 1;6(5):685-695. https://doi.org/10.1001/jamaoncol.2019.6716

  34. Merrigan SL, Park B, Ali Z, Jensen LD, Corson TW, Kennedy BN. Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo. Oncotarget. 2020 Feb 4;11(5):493-509. https://doi.org/10.18632/oncotarget.27380

  35. Whitmore H, Sishtla K, Knirsch W, Andriantiana JL, Schwikkard S, Mas-Claret E, Nassief SM, Isyaka SM, Corson TW, Mulholland DA. Bufadienolides and anti- angiogenic homoisoflavonoids from Rhodocodon cryptopodus, Rhodocodon rotundus and Rhodocodon cyathiformis. Fitoterapia. 2020 Mar;141:104479. https://doi.org/10.1016/j.fitote.2020.104479

  36. Heo M, Lee B, Sishtla K, Fei X, Lee S, Park S, Yuan Y, Lee S, Kwon S, Lee J, Kim S, Corson TW, Seo SY. Enantioselective synthesis of homoisoflavanones by asymmetric transfer hydrogenation and their biological evaluation for antiangiogenic activity. J Org Chem. 2019 Aug 16;84(16):9995-10011. https://doi.org/10.1021/acs.joc.9b01134

  37. Seo SY, Corson TW. Small molecule target identification using photo-affinity chromatography. Methods Enzymol. 2019;622:347-374. https://doi.org/10.1016/bs.mie.2019.02.028

  38. Schwikkard S, Whitmore H, Sishtla K, Sulaiman RS, Shetty T, Basavarajappa HD, Waller C, Alqahtani A, Frankemoelle L, Chapman A, Crouch N, Wetschnig W, Knirsch W, Andriantiana J, Mas-Claret E, Langat MK, Mulholland D, Corson TW. The antiangiogenic activity of naturally occurring and synthetic homoisoflavonoids from the Hyacinthaceae (sensu APGII). J Nat Prod. 2019 May 24;82(5):1227-1239. https://doi.org/10.1021/acs.jnatprod.8b00989

  39. Park B, Corson TW. Soluble epoxide hydrolase inhibition for ocular diseases: vision for the future. Front Pharmacol. 2019 Feb 7;10:95. https://doi.org/10.3389/fphar.2019.00095

  40. Bum-Erdene K, Zhou D, Gonzalez-Gutierrez G, Ghozayel MK, Si Y, Xu D, Shannon HE, Bailey BJ, Corson TW, Pollok KE, Wells CD, Meroueh SO. Small-molecule covalent modification of conserved cysteine leads to allosteric inhibition of the TEAD⋅Yap protein-protein interaction. Cell Chem Biol. 2019 Mar 21;26(3):378-389.e13. https://doi.org/10.1016/j.chembiol.2018.11.010

  41. Zhou D, Bum-Erdene K, Xu D, Liu D, Tompkins D, Sulaiman RS, Corson TW, Chirgwin JM, Meroueh SO. Small molecules inhibit ex vivo tumor growth in bone. Bioorg Med Chem. 2018 Dec 15;26(23-24):6128-6134. https://doi.org/10.1016/j.bmc.2018.11.025

  42. Sishtla K, Pitt N, Shadmand M, O'Hare MN, Sulaiman RS, Sinn AL, Condon K, Pollok KE, Sandusky GE, Corson TW. Observations on spontaneous tumor formation in mice overexpressing mitotic kinesin Kif14. Sci Rep. 2018 Nov 1;8(1):16152. https://doi.org/10.1038/s41598-018-34603-4

  43. Sardar Pasha SPB, Sishtla K, Sulaiman RS, Park B, Shetty T, Shah F, Fishel ML, Wikel JH, Kelley MR, Corson TW. Ref-1/APE1 inhibition with novel small molecules blocks ocular neovascularization. J Pharmacol Exp Ther. 2018 Oct;367(1):108-118. https://doi.org/10.1124/jpet.118.248088

  44. Schwikkard SL, Whitmore H, Corson TW, Sishtla K, Langat MK, Carew M, Mulholland DA. Antiangiogenic activity and cytotoxicity of triterpenoids and homoisoflavonoids from Massonia pustulata and Massonia bifolia. Planta Med. 2018 Jul;84(9-10):638-644. https://doi.org/10.1055/a-0577-5322

  45. Dimaras H, Corson TW. Retinoblastoma, the visible CNS tumor: A review. J Neurosci Res. 2019 Jan;97(1):29-44. https://doi.org/10.1002/jnr.24213

  46. Sulaiman RS, Park B, Sheik Pran Babu SP, Si Y, Kharwadkar R, Mitter SK, Lee B, Sun W, Qi X, Boulton ME, Meroueh SO, Fei X, Seo SY, Corson TW. Chemical proteomics reveals soluble epoxide hydrolase as a therapeutic target for ocular neovascularization. ACS Chem Biol. 2018 Jan 19;13(1):45-52. https://doi.org/10.1021/acschembio.7b00854

  47. Basavarajappa HD, Sulaiman RS, Qi X, Shetty T, Sheik Pran Babu S, Sishtla KL, Lee B, Quigley J, Alkhairy S, Briggs CM, Gupta K, Tang B, Shadmand M, Grant MB, Boulton ME, Seo SY, Corson TW. Ferrochelatase is a therapeutic target for ocular neovascularization. EMBO Mol Med. 2017 Jun;9(6):786-801. https://doi.org/10.15252/emmm.201606561

  48. Lee H, Yuan Y, Rhee I, Corson TW, Seo SY. Synthesis of natural homoisoflavonoids having either 5,7-dihydroxy-6-methoxy or 7-hydroxy-5,6-dimethoxy groups. Molecules. 2016 Aug 13;21(8):1058. https://doi.org/10.3390/molecules21081058

  49. Lee B, Sun W, Lee H, Basavarajappa H, Sulaiman RS, Sishtla K, Fei X, Corson TW, Seo SY. Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4277-81. https://doi.org/10.1016/j.bmcl.2016.07.043

  50. Racher H, Soliman S, Argiropoulos B, Chan HS, Gallie BL, Perrier R, Matevski D, Rushlow D, Piovesan B, Shaikh F, MacDonald H, Corson TW. Molecular analysis distinguishes metastatic disease from second cancers in patients with retinoblastoma. Cancer Genet. 2016 Jul-Aug;209(7-8):359-63. https://doi.org/10.1016/j.cancergen.2016.06.001

  51. O'Hare M, Shadmand M, Sulaiman RS, Sishtla K, Sakisaka T, Corson TW. Kif14 overexpression accelerates murine retinoblastoma development. Int J Cancer. 2016 Oct 15;139(8):1752-8. https://doi.org/10.1002/ijc.30221

  52. Sulaiman RS, Merrigan S, Quigley J, Qi X, Lee B, Boulton ME, Kennedy B, Seo SY, Corson TW. A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy. Sci Rep. 2016 May 5;6:25509. https://doi.org/10.1038/srep25509

  53. Sulaiman RS, Quigley J, Qi X, O'Hare MN, Grant MB, Boulton ME, Corson TW. A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization. J Ocul Pharmacol Ther. 2015 Oct;31(8):447-54. https://doi.org/10.1089/jop.2015.0049

  54. Hill JA, Lee SY, Njambi L, Corson TW, Dimaras H. Cancer genetics education in a low- to middle-income country: evaluation of an interactive workshop for clinicians in Kenya. PLoS One. 2015 Jun 2;10(6):e0129852. https://doi.org/10.1371/journal.pone.0129852

  55. Basavarajappa HD, Lee B, Lee H, Sulaiman RS, An H, Magaña C, Shadmand M, Vayl A, Rajashekhar G, Kim EY, Suh YG, Lee K, Seo SY, Corson TW. Synthesis and biological evaluation of novel homoisoflavonoids for retinal neovascularization. J Med Chem. 2015 Jun 25;58(12):5015-5027. https://doi.org/10.1021/acs.jmedchem.5b00449

  56. Wenzel AA, O'Hare MN, Shadmand M, Corson TW. Optical coherence tomography enables imaging of tumor initiation in the TAg-RB mouse model of retinoblastoma. Mol Vis. 2015 May 1;21:515-22. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440496/

  57.  Dimaras H, Corson TW, Cobrinik D, White A, Zhao J, Munier FL, Abramson DH, Shields CL, Chantada GL, Njuguna F, Gallie BL. Retinoblastoma. Nat Rev Dis Primers. 2015 Aug 27;1:15021. https://doi.org/10.1038/nrdp.2015.21

  58. Sulaiman RS, Basavarajappa HD, Corson TW. Natural product inhibitors of ocular angiogenesis. Exp Eye Res. 2014 Dec;129:161-71. https://doi.org/10.1016/j.exer.2014.10.002

  59. Lee B, Basavarajappa HD, Sulaiman RS, Fei X, Seo SY, Corson TW. The first synthesis of the antiangiogenic homoisoflavanone, cremastranone. Org Biomol Chem. 2014 Oct 21;12(39):7673-7. https://doi.org/10.1039/c4ob01604a

  60. Luo N, Conwell MD, Chen X, Kettenhofen CI, Westlake CJ, Cantor LB, Wells CD, Weinreb RN, Corson TW, Spandau DF, Joos KM, Iomini C, Obukhov AG, Sun Y. Primary cilia signaling mediates intraocular pressure sensation. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12871-6. https://doi.org/10.1073/pnas.1323292111

  61. Corson TW, Samuels BC, Wenzel AA, Geary AJ, Riley AA, McCarthy BP, Hanenberg H, Bailey BJ, Rogers PI, Pollok KE, Rajashekhar G, Territo PR. Multimodality imaging methods for assessing retinoblastoma orthotopic xenograft growth and development. PLoS One. 2014 Jun 5;9(6):e99036. https://doi.org/10.1371/journal.pone.0099036

  62. Singel SM, Cornelius C, Zaganjor E, Batten K, Sarode VR, Buckley DL, Peng Y, John GB, Li HC, Sadeghi N, Wright WE, Lum L, Corson TW, Shay JW. KIF14 promotes AKT phosphorylation and contributes to chemoresistance in triple-negative breast cancer. Neoplasia. 2014 Mar;16(3):247-56, 256.e2. https://doi.org/10.1016/j.neo.2014.03.008

  63. Basavarajappa HD, Lee B, Fei X, Lim D, Callaghan B, Mund JA, Case J, Rajashekhar G, Seo SY, Corson TW. Synthesis and mechanistic studies of a novel homoisoflavanone inhibitor of endothelial cell growth. PLoS One. 2014 Apr 21;9(4):e95694. https://doi.org/10.1371/journal.pone.0095694

  64. Thériault BL, Basavarajappa HD, Lim H, Pajovic S, Gallie BL, Corson TW. Transcriptional and epigenetic regulation of KIF14 overexpression in ovarian cancer. PLoS One. 2014 Mar 13;9(3):e91540. https://doi.org/10.1371/journal.pone.0091540

  65. Thériault BL, Dimaras H, Gallie BL, Corson TW. The genomic landscape of retinoblastoma: a review. Clin Exp Ophthalmol. 2014 Jan-Feb;42(1):33-52. https://doi.org/10.1111/ceo.12132

  66. Hines J, Gough JD, Corson TW, Crews CM. Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACs. Proc Natl Acad Sci U S A. 2013 May 28;110(22):8942-7. https://doi.org/10.1073/pnas.1217206110

  67. Rushlow DE, Mol BM, Kennett JY, Yee S, Pajovic S, Thériault BL, Prigoda-Lee NL, Spencer C, Dimaras H, Corson TW, Pang R, Massey C, Godbout R, Jiang Z, Zacksenhaus E, Paton K, Moll AC, Houdayer C, Raizis A, Halliday W, Lam WL, Boutros PC, Lohmann D, Dorsman JC, Gallie BL. Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies. Lancet Oncol. 2013 Apr;14(4):327-34. https://doi.org/10.1016/S1470-2045(13)70045-7

  68. Basavarajappa HD, Corson TW. KIF14 as an oncogene in retinoblastoma: a target for novel therapeutics? Future Med Chem. 2012 Nov;4(17):2149-52. https://doi.org/10.4155/fmc.12.158

  69. Temming P, Corson TW, Lohmann DR. Retinoblastoma tumorigenesis: genetic and epigenetic changes walk hand in hand. Future Oncol. 2012 May;8(5):525-8. https://doi.org/10.2217/fon.12.41

  70. Corson TW, Pajovic S, Dimaras H, Thériault BL, Gallie BL. Author response: Does the time of inactivation of pRb determine the cell of origin of retinoblastoma? Invest Ophthalmol Vis Sci. 2012 Feb 13;53(2):676. https://doi.org/10.1167/iovs.11-9371

  71. Pajovic S, Corson TW, Spencer C, Dimaras H, Orlic-Milacic M, Marchong MN, To KH, Thériault B, Auspitz M, Gallie BL. The TAg-RB murine retinoblastoma cell of origin has immunohistochemical features of differentiated Muller glia with progenitor properties. Invest Ophthalmol Vis Sci. 2011 Sep 29;52(10):7618-24. https://doi.org/10.1167/iovs.11-7989

  72. Neklesa TK, Tae HS, Schneekloth AR, Stulberg MJ, Corson TW, Sundberg TB, Raina K, Holley SA, Crews CM. Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins. Nat Chem Biol. 2011 Jul 3;7(8):538-43. https://doi.org/10.1038/nchembio.597

  73. Corson TW, Cavga H, Aberle N, Crews CM. Triptolide directly inhibits dCTP pyrophosphatase. Chembiochem. 2011 Jul 25;12(11):1767-73. https://doi.org/10.1002/cbic.201100007

  74. Uemura T, Green M, Corson TW, Perova T, Li PP, Warsh JJ. Bcl-2 SNP rs956572 associates with disrupted intracellular calcium homeostasis in bipolar I disorder. Bipolar Disord. 2011 Feb;13(1):41-51. https://doi.org/10.1111/j.1399-5618.2011.00897.x

  75. Buckley DL, Corson TW, Aberle N, Crews CM. HIV protease-mediated activation of sterically capped proteasome inhibitors and substrates. J Am Chem Soc. 2011 Feb 2;133(4):698-700. https://doi.org/10.1021/ja109377p

  76. Corson TW, Aberle N, Crews CM. Design and Applications of Bifunctional Small Molecules: Why Two Heads Are Better Than One. ACS Chem Biol. 2008 Nov 21;3(11):677-692. https://doi.org/10.1021/cb8001792

  77. Dimaras H, Khetan V, Halliday W, Orlic M, Prigoda NL, Piovesan B, Marrano P, Corson TW, Eagle RC Jr, Squire JA, Gallie BL. Loss of RB1 induces non- proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma. Hum Mol Genet. 2008 May 15;17(10):1363-72. https://doi.org/10.1093/hmg/ddn024

  78. Huang JC, Babak T, Corson TW, Chua G, Khan S, Gallie BL, Hughes TR, Blencowe BJ, Frey BJ, Morris QD. Using expression profiling data to identify human microRNA targets. Nat Methods. 2007 Dec;4(12):1045-9. https://doi.org/10.1038/nmeth1130

  79. Madhavan J, Coral K, Mallikarjuna K, Corson TW, Amit N, Khetan V, George R, Biswas J, Gallie BL, Kumaramanickavel G. High expression of KIF14 in retinoblastoma: association with older age at diagnosis. Invest Ophthalmol Vis Sci. 2007 Nov;48(11):4901-6. https://doi.org/10.1167/iovs.07-0063

  80. Corson TW, Crews CM. Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell. 2007 Sep 7;130(5):769-74. https://doi.org/10.1016/j.cell.2007.08.021

  81. Corson TW, Zhu CQ, Lau SK, Shepherd FA, Tsao MS, Gallie BL. KIF14 messenger RNA expression is independently prognostic for outcome in lung cancer. Clin Cancer Res. 2007 Jun 1;13(11):3229-34. https://doi.org/10.1158/1078-0432.CCR-07-0393

  82. Corson TW, Gallie BL. One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma. Genes Chromosomes Cancer. 2007 Jul;46(7):617-34. https://doi.org/10.1002/gcc.20457

  83. Bowles E, Corson TW, Bayani J, Squire JA, Wong N, Lai PB, Gallie BL. Profiling genomic copy number changes in retinoblastoma beyond loss of RB1. Genes Chromosomes Cancer. 2007 Feb;46(2):118-29. https://doi.org/10.1002/gcc.20383

  84. Corson TW, Gallie BL. KIF14 mRNA expression is a predictor of grade and outcome in breast cancer. Int J Cancer. 2006 Sep 1;119(5):1088-94. https://doi.org/10.1002/ijc.21954

  85. Spencer C, Pajovic S, Devlin H, Dinh QD, Corson TW, Gallie BL. Distinct patterns of expression of the RB gene family in mouse and human retina. Gene Expr Patterns. 2005 Jun;5(5):687-94. https://doi.org/10.1016/j.modgep.2005.02.003

  86. Corson TW, Huang A, Tsao MS, Gallie BL. KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers. Oncogene. 2005 Jul 14;24(30):4741-53. https://doi.org/10.1038/sj.onc.1208641

  87. Marchong MN, Chen D, Corson TW, Lee C, Harmandayan M, Bowles E, Chen N, Gallie BL. Minimal 16q genomic loss implicates cadherin-11 in retinoblastoma. Mol Cancer Res. 2004 Sep;2(9):495-503. https://doi.org/10.1158/1541-7786.495.2.9

  88. Corson TW, Woo KK, Li PP, Warsh JJ. Cell-type specific regulation of calreticulin and Bcl-2 expression by mood stabilizer drugs. Eur Neuropsychopharmacol. 2004 Mar;14(2):143-50. https://doi.org/10.1016/S0924-977X(03)00102-0

  89. Wasserman MJ, Corson TW, Sibony D, Cooke RG, Parikh SV, Pennefather PS, Li PP, Warsh JJ. Chronic lithium treatment attenuates intracellular calcium mobilization. Neuropsychopharmacology. 2004 Apr;29(4):759-69. https://doi.org/10.1038/sj.npp.1300400

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